Description
Udenafil is an inhibitor of phosphodiesterase 5 (PDE5). In vivo, udenafil increases lung cGMP levels, attenuates the development of compensatory right ventricular hypertrophy, and reduces pulmonary arterial wall thickening. It increases creatine clearance and decreases blood urea nitrogen (BUN) and serum malondialdehyde (MDA) levels in a rat model of renal ischemia-reperfusion injury. Udenafil also induces penile erections in conscious rabbits and in rabbits with acute spinal cord injury.
Product information
CAS Number: 268203-93-6
Molecular Weight: 516.66
Formula: C25H36N6O4S
Synonym:
DA8159
Zydena
Chemical Name: 3-{1-methyl-7-oxo-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-5-yl}-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzene-1-sulfonamide
Smiles: CN1CCCC1CCNS(=O)(=O)C1=CC(C2NC3=C(C(=O)N=2)N(C)N=C3CCC)=C(C=C1)OCCC
InChiKey: IYFNEFQTYQPVOC-UHFFFAOYSA-N
InChi: InChI=1S/C25H36N6O4S/c1-5-8-20-22-23(31(4)29-20)25(32)28-24(27-22)19-16-18(10-11-21(19)35-15-6-2)36(33,34)26-13-12-17-9-7-14-30(17)3/h10-11,16-17,26H,5-9,12-15H2,1-4H3,(H,27,28,32)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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