Description
PROTAC ERRα Degrader-2 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-2 is an estrogen-related receptor alpha (ERRa) degrader.
Product information
CAS Number: 2306388-85-0
Molecular Weight: 1150.99
Formula: C57H55Cl2F6N7O8
Chemical Name: (E)-N-(5-(2-(4-((4R, 5S)-4, 5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4, 5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetamido)pentyl)-3-(4-((2, 4-bis(trifluoromethyl)benzyl)oxy)-3-methoxyphenyl)-2-cyanoacrylamide
Smiles: CC(C)OC1C=C(C=CC=1C1=N[C@@H]([C@H](C2C=CC(Cl)=CC=2)N1C(=O)N1CC(=O)N(CC(=O)NCCCCCNC(=O)/C(=C/C2=CC(OC)=C(C=C2)OCC2C=CC(=CC=2C(F)(F)F)C(F)(F)F)/C#N)CC1)C1C=CC(Cl)=CC=1)OC
InChiKey: BCMRBUQELZGQDK-ZAZFVFGXSA-N
InChi: InChI=1S/C57H55Cl2F6N7O8/c1-34(2)80-47-29-43(77-3)19-20-44(47)53-69-51(36-10-15-41(58)16-11-36)52(37-12-17-42(59)18-13-37)72(53)55(76)71-25-24-70(50(74)32-71)31-49(73)67-22-6-5-7-23-68-54(75)39(30-66)26-35-8-21-46(48(27-35)78-4)79-33-38-9-14-40(56(60,61)62)28-45(38)57(63,64)65/h8-21,26-29,34,51-52H,5-7,22-25,31-33H2,1-4H3,(H,67,73)(H,68,75)/b39-26+/t51-,52+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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