Description
Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).
Product information
CAS Number: 245443-52-1
Molecular Weight: 666.77
Formula: C33H46N8O7
Chemical Name: 1-[2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoyl]-N-[2-[[6-amino-1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]pyrrolidine-2-carboxamide
Smiles: NC(=O)C(CC1C=CC=CC=1)NC(=O)C(CCCCN)NC(=O)CNC(=O)C1CCCN1C(=O)C(CC1C=CC(O)=CC=1)NC(=O)CN
InChiKey: NAIYNSCJEHHFMV-UHFFFAOYSA-N
InChi: InChI=1S/C33H46N8O7/c34-15-5-4-9-24(31(46)40-25(30(36)45)17-21-7-2-1-3-8-21)38-29(44)20-37-32(47)27-10-6-16-41(27)33(48)26(39-28(43)19-35)18-22-11-13-23(42)14-12-22/h1-3,7-8,11-14,24-27,42H,4-6,9-10,15-20,34-35H2,(H2,36,45)(H,37,47)(H,38,44)(H,39,43)(H,40,46)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 50 mg/mL (74.99 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
GYPGKF-NH2 significantly reduces the agonistic potency of AYPGKF-NH2 by 25-fold. GYPGKF-NH2 (500 μM) does not cause contraction or relaxation of the guinea pig IAS strips.
Products are for research use only. Not for human use.
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