Description
AGN 205728 is a potent and selective RARγ antagonist.
Product information
CAS Number: 859498-05-8
Molecular Weight: 437.53
Formula: C29H27NO3
Synonym:
AGN205728
AGN-205728
Chemical Name: 4-[(1E,3E)-3-[8,8-dimethyl-5-(4-methylphenyl)-7,8-dihydronaphthalen-2-yl]-3-(hydroxyimino)prop-1-en-1-yl]benzoic acid
Smiles: CC1C=CC(=CC=1)C1=CCC(C)(C)C2=CC(=CC=C12)/C(/C=C/C1C=CC(=CC=1)C(O)=O)=N/O
InChiKey: AUKGBKLQWDXBEP-FSLFYVJCSA-N
InChi: InChI=1S/C29H27NO3/c1-19-4-9-21(10-5-19)24-16-17-29(2,3)26-18-23(13-14-25(24)26)27(30-33)15-8-20-6-11-22(12-7-20)28(31)32/h4-16,18,33H,17H2,1-3H3,(H,31,32)/b15-8+,30-27+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Tsang, Kwok Yin, et al. Preparation of disubstituted chalcone oximes having RARγ retinoid receptor antagonist activity. Appl. (2005), WO 2005066115 A2 20050721.
Products are for research use only. Not for human use.
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