GRL-0496 - CAS# 1087243-14-8


Catalog No. Size PriceQuantity
M17317-C Contact sales@xcessbio.com for quotation $100

Description

GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM.

Product information

CAS Number: 1087243-14-8

Molecular Weight: 272.69

Formula: C14H9ClN2O2

Chemical Name: 5-chloropyridin-3-yl 1H-indole-4-carboxylate

Smiles: O=C(OC1=CN=CC(Cl)=C1)C1C=CC=C2NC=CC=12

InChiKey: BOSZJNSICHFHMA-UHFFFAOYSA-N

InChi: InChI=1S/C14H9ClN2O2/c15-9-6-10(8-16-7-9)19-14(18)12-2-1-3-13-11(12)4-5-17-13/h1-8,17H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

GRL-0496 shows the best SARS-CoV antiviral activity, with an EC EC50 of 6.9 μM.

Products are for research use only. Not for human use.

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