Description
Pamidronate disodium pentahydrate is a nitrogen-containing bisphosphonate, used to prevent osteoporosis.
Product information
CAS Number: 109552-15-0
Molecular Weight: 369.11
Formula: C3H19NNa2O12P2
Chemical Name: (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid hydrate sodium
Smiles: O.O.O.O.O.[Na+].[Na+].NCCC(O)(P([O-])(O)=O)P([O-])(O)=O
InChiKey: CZYWHNTUXNGDGR-UHFFFAOYSA-L
InChi: InChI=1S/C3H11NO7P2.2Na.5H2O/c4-2-1-3(5,12(6,7)8)13(9,10)11;;;;;;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;;5*1H2/q;2*+1;;;;;/p-2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 7.14 mg/mL (19.34 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Kubalek I, et al. Treatment of reflex sympathetic dystrophy with pamidronate: 29 cases. Rheumatology (Oxford). 2001 Dec;40(12):1394-7.
- Zarychanski R, et al. Osteonecrosis of the jaw associated with pamidronate therapy. Am J Hematol. 2006 Jan;81(1):73-5.
Products are for research use only. Not for human use.
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