Ethacizine hydrochloride - CAS# 57530-40-2


Catalog No. Size PriceQuantity
M17465-C Contact sales@xcessbio.com for quotation $100

Description

Ethacizine hydrochloride (Ethacizin; NIK-244) is a longer-lasting Class Ic antiarrhythmic agent than Flecainide. Ethacizine hydrochloride (Ethacizin; NIK-244) inhibits the depolarizing current responsible for the intraatrial and His-Purkinje-ventricular conduction.

Product information

CAS Number: 57530-40-2

Molecular Weight: 449.99

Formula: C22H28ClN3O3S

Chemical Name: ethyl N-{10-[3-(diethylamino)propanoyl]-10H-phenothiazin-2-yl}carbamate hydrochloride

Smiles: Cl.CCOC(=O)NC1=CC2=C(C=C1)SC1C=CC=CC=1N2C(=O)CCN(CC)CC

InChiKey: VHNXQKLWIQHSOY-UHFFFAOYSA-N

InChi: InChI=1S/C22H27N3O3S.ClH/c1-4-24(5-2)14-13-21(26)25-17-9-7-8-10-19(17)29-20-12-11-16(15-18(20)25)23-22(27)28-6-3;/h7-12,15H,4-6,13-14H2,1-3H3,(H,23,27);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

NIK-244 (1-300 ug) injects directly into the SA node and PM preparations shows negative chronotropic, negative inotropic and coronary vasodilator.

Products are for research use only. Not for human use.

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