Description
TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively .
Product information
CAS Number: 1950628-94-0
Molecular Weight: 362.40
Formula: C20H17N5O2
Chemical Name: N-(4-{3-[5-(²H₃)methoxypyridin-2-yl]-1H-pyrrolo[3,2-b]pyridin-2-yl}pyridin-2-yl)acetamide
Smiles: [2H]C([2H])([2H])OC1=CN=C(C=C1)C1C2=NC=CC=C2NC=1C1=CC(NC(C)=O)=NC=C1
InChiKey: VRPRBQAJAQCSCW-BMSJAHLVSA-N
InChi: InChI=1S/C20H17N5O2/c1-12(26)24-17-10-13(7-9-21-17)19-18(15-6-5-14(27-2)11-23-15)20-16(25-19)4-3-8-22-20/h3-11,25H,1-2H3,(H,21,24,26)/i2D3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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