Description
Hydrochlorothiazide is a first line diuretic compound of the thiazide class.
Product information
CAS Number: 58-93-5
Molecular Weight: 297.74
Formula: C7H8ClN3O4S2
Synonym:
Hypothiazide
Dichlotride
Hydrosaluric
Esidrex
Sectrazide
Dichlothiazide
Dihydrochlorothiazide
HCTZ
HydroDIURIL
Oretic
Chemical Name: 6-chloro-1,1-dioxo-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide
Smiles: NS(=O)(=O)C1=CC2=C(C=C1Cl)NCNS2(=O)=O
InChiKey: JZUFKLXOESDKRF-UHFFFAOYSA-N
InChi: InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO, not in water
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
References:
- Dinç E, Ertekin ZC. Three-way analysis of the UPLC-PDA dataset for themulticomponent quantitation of hydrochlorothiazide and olmesartan medoxomil intablets by parallel factor analysis and three-way partial least squares. Talanta.2016 Feb 1;148:144-52. doi: 10.1016/j.talanta.2015.10.074. Epub 2015 Oct 26.PubMed PMID: 26653435.
- Machini WB, David-Parra DN, Teixeira MF. Electrochemical investigation of thevoltammetric determination of hydrochlorothiazide using a nickel hydroxidemodified nickel electrode. Mater Sci Eng C Mater Biol Appl. 2015 Dec 1;57:344-8.doi: 10.1016/j.msec.2015.07.035. Epub 2015 Aug 11. PubMed PMID: 26354274.
- Arafa MF, El-Gizawy SA, Osman MA, El Maghraby GM. Sucralose as co-crystalco-former for hydrochlorothiazide: development of oral disintegrating tablets.Drug Dev Ind Pharm. 2015 Dec 7:1-9. [Epub ahead of print] PubMed PMID: 26555927.
Products are for research use only. Not for human use.
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