Description
RN-1734 is selective antagonist of the TRPV4 channel completely antagonizes 4PDD-mediated activation of TRPV4 with comparable low micromolar IC50 values for all three species hTRPV4 IC50 23 M mTRPV4 IC50 59 M rTRPV4 IC50 32 M
Product information
CAS Number: 946387-07-1
Molecular Weight: 353.31
Formula: C14H22Cl2N2O2S
Chemical Name: 2,4-dichloro-N-(propan-2-yl)-N-{2-[(propan-2-yl)amino]ethyl}benzene-1-sulfonamide
Smiles: CC(C)N(CCNC(C)C)S(=O)(=O)C1=CC=C(Cl)C=C1Cl
InChiKey: IHYZMEAZAIFMTN-UHFFFAOYSA-N
InChi: InChI=1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 71 mg/mL(200.95 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Liu M, et al. Front Cell Neurosci. 2018 Nov 5;12:392.
- Vincent F, et al. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.