Levosimendan


Catalog No. Size PriceQuantity
M10424-2 Solid 2 mg $80
M10424-10 Solid 10 mg $240

Description

Levosimendan is a calcium sensitizer that can cause increased cardiac contractility by binding troponin C, promotes vasodilation by activating ATP-sensitive potassium channels on vascular smooth muscle cells, and performs a cardioprotective function by prompting the opening of mitochondrial potassium channels in cardiomyocytes. It also has been reported to inhibit phosphodiesterases 3 and 4 in left ventricular cardiac tissue.

Product information

CAS Number: 141505-33-1

Molecular Weight: 280.28

Formula: C14H12N6O

Chemical Name: 1-cyano-N-{4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}methanecarbohydrazonoyl cyanide

Smiles: C[C@@H]1CC(=O)NN=C1C1C=CC(=CC=1)NN=C(C#N)C#N

InChiKey: WHXMKTBCFHIYNQ-SECBINFHSA-N

InChi: InChI=1S/C14H12N6O/c1-9-6-13(21)19-20-14(9)10-2-4-11(5-3-10)17-18-12(7-15)8-16/h2-5,9,17H,6H2,1H3,(H,19,21)/t9-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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