Rucaparib phosphate - CAS# 459868-92-9


Catalog No. Size PriceQuantity
M10543-2 Solid 2 mg $85
M10543-10 Solid 10 mg $255

Description

Rucaparib is a tricyclic indole poly(ADP-Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Rucaparib selectively binds to PARP1 and inhibits PARP1-mediated DNA repair, thereby enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis.

Product information

CAS Number: 459868-92-9

Molecular Weight: 421.36

Formula: C19H21FN3O5P

Synonym:

AG014699 phosphate

PF01367338 phosphate

AG 014699 phosphate

PF 01367338 phosphate

AG-014699 phosphate

PF-01367338 phosphate

Chemical Name: 6-fluoro-2-{4-[(methylamino)methyl]phenyl}-3,10-diazatricyclo[6.4.1.0⁴,¹³]trideca-1,4,6,8(13)-tetraen-9-one; phosphoric acid

Smiles: CNCC1=CC=C(C=C1)C1NC2=CC(F)=CC3=C2C=1CCNC3=O.OP(O)(O)=O

InChiKey: FCCGJTKEKXUBFZ-UHFFFAOYSA-N

InChi: InChI=1S/C19H18FN3O.H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15;1-5(2,3)4/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24);(H3,1,2,3,4)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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