Description
Vaniprevir, also known as MK7009, is a macrocyclic hepatitis C virus (HCV) NS3/4a protease inhibitor. Vaniprevir is active against both the genotype 1 and genotype 2 NS3/4a protease enzymes and has good plasma exposure and excellent liver exposure in multiple species. Vaniprevir is a potent HCV protease inhibitor with a predictable resistance profile and favorable safety profile that is suitable for QD or BID administration. In Japan, it was approved for treating hepatitis C in 2014.
Product information
CAS Number: 923590-37-8
Molecular Weight: 757.94
Formula: C38H55N5O9S
Chemical Name: (1R,21S,24S)-21-tert-butyl-N-[(1R,2R)-1-[(cyclopropanesulfonyl)carbamoyl]-2-ethylcyclopropyl]-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.1⁴,⁷.0⁶,¹¹]heptacosa-6(11),7,9-triene-24-carboxamide
Smiles: CC(C)(C)[C@@H]1NC(=O)OCC(C)(C)CCCCC2=CC=CC3CN(CC2=3)C(=O)O[C@@H]2C[C@@H](C(=O)N[C@@]3(C[C@H]3CC)C(=O)NS(=O)(=O)C3CC3)N(C2)C1=O
InChiKey: KUQWGLQLLVFLSM-ONAXAZCASA-N
InChi: InChI=1S/C38H55N5O9S/c1-7-25-18-38(25,33(46)41-53(49,50)27-14-15-27)40-31(44)29-17-26-20-43(29)32(45)30(36(2,3)4)39-34(47)51-22-37(5,6)16-9-8-11-23-12-10-13-24-19-42(21-28(23)24)35(48)52-26/h10,12-13,25-27,29-30H,7-9,11,14-22H2,1-6H3,(H,39,47)(H,40,44)(H,41,46)/t25-,26-,29+,30-,38-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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