Description
Sumanirole, also known as PNU-95666, is a highly selective D2 receptor full agonist, the first of its kind to be discovered. It was developed for the treatment of Parkinson's disease and restless leg syndrome. While it has never been approved for medical use, it is a highly valuable tool compound for basic research to identify neurobiological mechanisms that are based on a dopamine D2-linked (vs. D1, D3, D4, and D5-linked) mechanism of action.
Product information
CAS Number: 179386-44-8
Molecular Weight: 319.31
Formula: C15H17N3O5
Synonym:
U95666E
PNU 95666
PNU 95666E
Sumanirole
Chemical Name: (10R)-10-(methylamino)-1,3-diazatricyclo[6.3.1.0⁴,¹²]dodeca-4,6,8(12)-trien-2-one; (2Z)-but-2-enedioic acid
Smiles: CN[C@@H]1CC2=CC=CC3NC(=O)N(C1)C2=3.OC(=O)/C=C\C(O)=O
InChiKey: VOJRMYBBPKNLLI-ORHWHDKWSA-N
InChi: InChI=1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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