Description
OGG1-IN-08 (O8 OGG1 Inhibitor-Bio-X) is a potent inhibitor of 8-oxoguanine DNA glycosylase-1 (OGG1) with IC50 of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1.
Product information
CAS Number: 350997-39-6
Molecular Weight: 261.13
Formula: C9H6Cl2N2OS
Chemical Name: 3, 4-dichloro-1-benzothiophene-2-carbohydrazide
Smiles: NNC(=O)C1SC2=CC=CC(Cl)=C2C=1Cl
InChiKey: HSSHUDKWJRJKPV-UHFFFAOYSA-N
InChi: InChI=1S/C9H6Cl2N2OS/c10-4-2-1-3-5-6(4)7(11)8(15-5)9(14)13-12/h1-3H,12H2,(H,13,14)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Solubility (25°C) DMSO: 52 mg/mL(199.13 mM). Water: Insoluble.
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Nathan Donley, et al. ACS Chem Biol. 2015 Oct 16;10(10):2334-43.
Products are for research use only. Not for human use.
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