Description
FX-11 (LDHA Inhibitor FX11) is a potent lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 23.3 μM for HeLa cell and a Ki value of 8 μM.
Product information
CAS Number: 213971-34-7
Molecular Weight: 350.41
Formula: C22H22O4
Synonym:
LDHA Inhibitor FX11
Chemical Name: 7-benzyl-2, 3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid
Smiles: CC1=CC2=C(C=C1CC1C=CC=CC=1)C(C(O)=O)=C(O)C(O)=C2CCC
InChiKey: LVPYVYFMCKYFCZ-UHFFFAOYSA-N
InChi: InChI=1S/C22H22O4/c1-3-7-16-17-10-13(2)15(11-14-8-5-4-6-9-14)12-18(17)19(22(25)26)21(24)20(16)23/h4-6,8-10,12,23-24H,3,7,11H2,1-2H3,(H,25,26)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 250 mg/mL (713.45 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- EMILIA C. CALVARESI, et al. SMALL MOLECULE INHIBITORS OF LACTATE DEHYDROGENASE A AS AN ANTICANCER STRATEGY.
Products are for research use only. Not for human use.
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