PARP14 inhibitor H10


Catalog No. Size PriceQuantity
M12583-2 2mg solid $755
M12583-10 10mg solid $3,020

Description

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis.

Product information

CAS Number: 2084811-68-5

Molecular Weight: 557.58

Formula: C24H27N7O7S

Chemical Name: 3-({2-[4-(2-{3-[(3-carbamoylphenyl)carbamoyl]propanamido}ethyl)-1H-1, 2, 3-triazol-1-yl]ethyl}sulfamoyl)benzoic acid

Smiles: NC(=O)C1=CC(=CC=C1)NC(=O)CCC(=O)NCCC1=CN(CCNS(=O)(=O)C2=CC(=CC=C2)C(O)=O)N=N1

InChiKey: MUOMSHSMJCWQFH-UHFFFAOYSA-N

InChi: InChI=1S/C24H27N7O7S/c25-23(34)16-3-1-5-18(13-16)28-22(33)8-7-21(32)26-10-9-19-15-31(30-29-19)12-11-27-39(37,38)20-6-2-4-17(14-20)24(35)36/h1-6,13-15,27H,7-12H2,(H2,25,34)(H,26,32)(H,28,33)(H,35,36)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 62.5 mg/mL (112.09 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed