LSD1-IN-6


Catalog No. Size PriceQuantity
M13230-2 Contact sales@xcessbio.com for quotation $100
M13230-10 Contact sales@xcessbio.com for quotation $100

Description

LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1.

Product information

CAS Number: 2035912-43-5

Molecular Weight: 349.18

Formula: C15H13BrN2O3

Chemical Name: (Z)-4-[(E)-2-(2-bromo-4,5-dihydroxyphenyl)ethenyl]-N'-hydroxybenzene-1-carboximidamide

Smiles: N/C(=N\O)/C1C=CC(/C=C/C2=CC(O)=C(O)C=C2Br)=CC=1

InChiKey: JDEDYOAMPIVKCF-ZZXKWVIFSA-N

InChi: InChI=1S/C15H13BrN2O3/c16-12-8-14(20)13(19)7-11(12)6-3-9-1-4-10(5-2-9)15(17)18-21/h1-8,19-21H,(H2,17,18)/b6-3+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.

Products are for research use only. Not for human use.

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