Description
Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid with antiproliferative and antitumour activities. Ethyl Orsellinate is against A. salina for the cytotoxic activity with an LC50 of 495 μM.
Product information
CAS Number: 2524-37-0
Molecular Weight: 196.20
Formula: C10H12O4
Chemical Name: ethyl 2,4-dihydroxy-6-methylbenzoate
Smiles: CC1C=C(O)C=C(O)C=1C(=O)OCC
InChiKey: UQSRXQMIXSZGLA-UHFFFAOYSA-N
InChi: InChI=1S/C10H12O4/c1-3-14-10(13)9-6(2)4-7(11)5-8(9)12/h4-5,11-12H,3H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Ethyl Orsellinate (0-50 μg/ml; 48 hours) inhibits Hep-2 cells, MCF-7 breast cancer cells, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s=31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively).
References:
- Bogo D, et al. In vitro antitumour activity of orsellinates. Z Naturforsch C. 2010 Jan-Feb;65(1-2):43-8.
- Gomes AT, et al. Cytotoxic activity of orsellinates. Z Naturforsch C. 2006 Sep-Oct;61(9-10):653-7.
Products are for research use only. Not for human use.
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