(R)-ADX-47273


Catalog No. Size PriceQuantity
M14484-2 Contact sales@xcessbio.com for quotation $100

Description

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .

Product information

CAS Number: 851881-59-9

Molecular Weight: 369.36

Formula: C20H17F2N3O2

Chemical Name: (3R)-1-(4-fluorobenzoyl)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]piperidine

Smiles: O=C(C1C=CC(F)=CC=1)N1C[C@@H](CCC1)C1=NC(=NO1)C1C=CC(F)=CC=1

InChiKey: VXQCCZHCFBHTTD-OAHLLOKOSA-N

InChi: InChI=1S/C20H17F2N3O2/c21-16-7-3-13(4-8-16)18-23-19(27-24-18)15-2-1-11-25(12-15)20(26)14-5-9-17(22)10-6-14/h3-10,15H,1-2,11-12H2/t15-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

(R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM.

Products are for research use only. Not for human use.

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