Description
VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders.
Product information
CAS Number: 2180914-37-6
Molecular Weight: 439.41
Formula: C17H16F3N7O2S
Chemical Name: 5-amino-3-methoxy-4-methyl-N-{1-[5-(trifluoromethyl)pyrimidin-2-yl]azetidin-3-yl}thieno[2,3-c]pyridazine-6-carboxamide
Smiles: CC1C(=NN=C2SC(=C(N)C=12)C(=O)NC1CN(C1)C1=NC=C(C=N1)C(F)(F)F)OC
InChiKey: VILQHBIGBISKQM-UHFFFAOYSA-N
InChi: InChI=1S/C17H16F3N7O2S/c1-7-10-11(21)12(30-15(10)26-25-14(7)29-2)13(28)24-9-5-27(6-9)16-22-3-8(4-23-16)17(18,19)20/h3-4,9H,5-6,21H2,1-2H3,(H,24,28)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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