FAK ligand-Linker Conjugate 1


Catalog No. Size PriceQuantity
M14709-2 Contact sales@xcessbio.com for quotation $100

Description

FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation.

Product information

CAS Number: 2307461-45-4

Molecular Weight: 583.58

Formula: C25H28F3N5O6S

Chemical Name: 3-[2-(4-{[4-({[3-(N-methylmethanesulfonamido)phenyl]methyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenoxy)ethoxy]propanoic acid

Smiles: CN(C1=CC(CNC2=NC(NC3C=CC(=CC=3)OCCOCCC(O)=O)=NC=C2C(F)(F)F)=CC=C1)S(C)(=O)=O

InChiKey: OSVHAJNGZCDBGV-UHFFFAOYSA-N

InChi: InChI=1S/C25H28F3N5O6S/c1-33(40(2,36)37)19-5-3-4-17(14-19)15-29-23-21(25(26,27)28)16-30-24(32-23)31-18-6-8-20(9-7-18)39-13-12-38-11-10-22(34)35/h3-9,14,16H,10-13,15H2,1-2H3,(H,34,35)(H2,29,30,31,32)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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