Description
(R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.
Product information
Molecular Weight: 501.62
Formula: C28H28FN5OS
Chemical Name: 1-[(2R)-2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-3-phenylpropyl]-2',3'-dihydro-1'H-spiro[piperidine-4,4'-quinazolin]-2'-one
Smiles: O=C1NC2C=CC=CC=2C2(CCN(C[C@@H](CC3C=CC=CC=3)NC3=NC4=CC=C(F)C=C4S3)CC2)N1
InChiKey: FZOFDZMKSAUTHT-OAQYLSRUSA-N
InChi: InChI=1S/C28H28FN5OS/c29-20-10-11-24-25(17-20)36-27(32-24)30-21(16-19-6-2-1-3-7-19)18-34-14-12-28(13-15-34)22-8-4-5-9-23(22)31-26(35)33-28/h1-11,17,21H,12-16,18H2,(H,30,32)(H2,31,33,35)/t21-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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