Description
2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
Product information
CAS Number: 303-38-8
Molecular Weight: 154.12
Formula: C7H6O4
Synonym:
Catecholcarboxylic acid
NSC 27435
Chemical Name: 2,3-dihydroxybenzoic acid
Smiles: OC(=O)C1C=CC=C(O)C=1O
InChiKey: GLDQAMYCGOIJDV-UHFFFAOYSA-N
InChi: InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Solubility (25°C). 30 mg/mL(194.65 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
2,3-dihydroxyhenzoic acid (2,3-DHB) is an orally effective iron-chelating agent in hypertransfused rat. The iron excreted in response tc 2,3-DHB is excreted via the urine. The oral administration of 2,3-DHB decreases time absorption of iron (59FeCl3) by the gut. The LD5O of 2,3-DHB is greater than 3 g/kg in the rabbit. Rats and mice administered up to 600 mg/kg chronically have shown no signs of toxicity.
References:
- Grootveld M, et al. 2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism. Biochem Pharmacol. 1988 Jan 15;37(2):271-80.
Products are for research use only. Not for human use.
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