Description
Vps34-IN-1 is an inhibitor of Vps34 extracted from patent WO2012085815A1, compound example 16a, with an IC50 of 4 nM. Vps34-IN-1 modulates autophagy.
Product information
CAS Number: 1383716-33-3
Molecular Weight: 425.91
Formula: C21H24ClN7O
Chemical Name: 1-({2-[(2-chloropyridin-4-yl)amino]-4'-(cyclopropylmethyl)-[4,5'-bipyrimidin]-2'-yl}amino)-2-methylpropan-2-ol
Smiles: CC(C)(O)CNC1N=C(CC2CC2)C(=CN=1)C1=CC=NC(NC2C=C(Cl)N=CC=2)=N1
InChiKey: AWNXKZVIZARMME-UHFFFAOYSA-N
InChi: InChI=1S/C21H24ClN7O/c1-21(2,30)12-26-19-25-11-15(17(29-19)9-13-3-4-13)16-6-8-24-20(28-16)27-14-5-7-23-18(22)10-14/h5-8,10-11,13,30H,3-4,9,12H2,1-2H3,(H,25,26,29)(H,23,24,27,28)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 31 mg/mL (72.79 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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