Zinterol


Catalog No. Size PriceQuantity
M15314-2 Contact sales@xcessbio.com for quotation $100

Description

Zinterol (MJ 9184) is a potent and selective β2-adrenoceptor agonist. Zinterol increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM.

Product information

CAS Number: 37000-20-7

Molecular Weight: 378.49

Formula: C19H26N2O4S

Chemical Name: N-(2-hydroxy-5-{1-hydroxy-2-[(2-methyl-1-phenylpropan-2-yl)amino]ethyl}phenyl)methanesulfonamide

Smiles: CC(C)(CC1C=CC=CC=1)NCC(O)C1C=C(NS(C)(=O)=O)C(O)=CC=1

InChiKey: XJBCFFLVLOPYBV-UHFFFAOYSA-N

InChi: InChI=1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 38 mg/mL (100.40 mM; Need ultrasonic and warming). H2O : 1.89 mg/mL (4.99 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Zinterol (2.5 μg/kg i.v. bolus over 5 s) leads to ventricular arrhythmias including premature ventricular complexes (PVCs) and runs of ventricular tachycardia (VT) in heart failure (HF) rabbits. Zinterol at a lower dose (1 μg/kg i.v, n=4) does not induce ventricular arrhythmias in HF rabbits.

Products are for research use only. Not for human use.

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