Vasicinone


Catalog No. Size PriceQuantity
M15690-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Vasicinone is a quinazoline alkaloid isolated from the Adhatoda vasica plant. Vasicinone is a potential agent for Parkinson's disease and possibly other oxidative stress-related neurodegenerative disorders.

Product information

CAS Number: 486-64-6

Molecular Weight: 202.21

Formula: C11H10N2O2

Chemical Name: (S)-3-hydroxy-2, 3-dihydropyrrolo[2, 1-b]quinazolin-9(1H)-one

Smiles: O[C@H]1CCN2C(=O)C3=CC=CC=C3N=C21

InChiKey: SDIVYZXRQHWCKF-VIFPVBQESA-N

InChi: InChI=1S/C11H10N2O2/c14-9-5-6-13-10(9)12-8-4-2-1-3-7(8)11(13)15/h1-4,9,14H,5-6H2/t9-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Vasicinone (1~30 µM; 24 hours; SH-SY5Y cells) significantly reverses the paraquat-induced reduction in cell viability. Vasicinone (10 and 15 μM; 24 hours; SH-SY5Y cells) abates the paraquat-induced injury of SH-SY5Y cells by suppressing the MAPK signaling pathway, dose-dependently reduces the percentage of apoptotic cells and is capable of rescuing paraquat-induced apoptotic death. Vasicinone (10 and 15 μM; SH-SY5Y cells) attenuates the paraquat-induced accumulation of reactive oxygen species (ROS) and attenuates the paraquat-induced expression of apoptotic proteins.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed