(E/Z)-GSK-3β inhibitor 1


Catalog No. Size PriceQuantity
M16070-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM.

Product information

CAS Number: 3367-88-2

Molecular Weight: 222.24

Formula: C14H10N2O

Chemical Name: 3-(pyridin-2-ylmethylene)indolin-2-one

Smiles: O=C1NC2=CC=CC=C2C1=CC1=CC=CC=N1

InChiKey: YKQONSWBHGBDSB-XFXZXTDPSA-N

InChi: InChI=1S/C14H10N2O/c17-14-12(9-10-5-3-4-8-15-10)11-6-1-2-7-13(11)16-14/h1-9H,(H,16,17)/b12-9-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (224.98 mM; Need ultrasonic). H2O : < 0.1 mg/mL (insoluble).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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