Description
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress.
Product information
CAS Number: 3796-63-2
Molecular Weight: 330.55
Formula: C23H38O
Chemical Name: (5E, 9E, 13E)-6, 10, 14, 18-tetramethylnonadeca-5, 9, 13, 17-tetraen-2-one
Smiles: CC(C)=CCC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CCC(C)=O
InChiKey: HUCXKZBETONXFO-NJFMWZAGSA-N
InChi: InChI=1S/C23H38O/c1-19(2)11-7-12-20(3)13-8-14-21(4)15-9-16-22(5)17-10-18-23(6)24/h11,13,15,17H,7-10,12,14,16,18H2,1-6H3/b20-13+,21-15+,22-17+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 5 mg/mL (15.13 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
(5E,9E,13E)-Teprenone might transiently activate the transcription of HSP70 gene. The heat shock element–binding activity reflects the activation of heat shock factor 1 in response to (5E,9E,13E)-Teprenone.
In Vivo:
(5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa.
Products are for research use only. Not for human use.
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