GSK097 - CAS# 2159137-02-5


Catalog No. Size PriceQuantity
M16161-C Contact sales@xcessbio.com for quotation $100

Description

GSK097 is a potent and selective Inhibitor of the second bromodomain (BD2) of the bromodomain and extra-terminal domain (BET) proteins. GSK097 displays 2000-fold selective for BD2 over BD1 (BRD4 data) with >1 mg/mL solubility in FaSSIF media.

Product information

CAS Number: 2159137-02-5

Molecular Weight: 339.39

Formula: C19H21N3O3

Chemical Name: 6-[(S)-hydroxy(phenyl)methyl]-N2-methyl-N4-[(1S, 2S)-2-methylcyclopropyl]pyridine-2, 4-dicarboxamide

Smiles: C[C@H]1C[C@@H]1NC(=O)C1=CC(=NC(=C1)[C@@H](O)C1=CC=CC=C1)C(=O)NC

InChiKey: OJSKWCXPUVTNCF-YLVFBTJISA-N

InChi: InChI=1S/C19H21N3O3/c1-11-8-14(11)22-18(24)13-9-15(21-16(10-13)19(25)20-2)17(23)12-6-4-3-5-7-12/h3-7,9-11,14,17,23H,8H2,1-2H3,(H,20,25)(H,22,24)/t11-,14-,17-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

GSK097 displays pIC50s 7.4, 8.0, 7.6, and 7.9 for BRD2 BD2, BRD3 BD2, BRD4 BD2 and BRDT BD2, respectively.

Products are for research use only. Not for human use.

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