Description
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system.
Product information
CAS Number: 41372-08-1
Molecular Weight: 238.24
Formula: C20H32N2O11
Chemical Name: (S)-2-amino-3-(3, 4-dihydroxyphenyl)-2-methylpropanoic acid sesquihydrate
Smiles: O.O.O.C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O.C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O
InChiKey: YKFCISHFRZHKHY-NGQGLHOPSA-N
InChi: InChI=1S/2C10H13NO4.3H2O/c2*1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6;;;/h2*2-4,12-13H,5,11H2,1H3,(H,14,15);3*1H2/t2*10-;;;/m00.../s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 33.33 mg/mL (139.90 mM; Need ultrasonic). H2O : 1 mg/mL (4.20 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.
Products are for research use only. Not for human use.
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