Description
XQN70430, also known as MC-Ala-Ala-Asn(Trt)-PAB, is a hetero bifunctional cross-linker, useful in antibody drug conjugation (ADC). XQN70430 is a fissionable linker which is specifically activated in a tumor microenvironment. XQN70430 was reported in patent WO 2016026458. This product has no formal name at the moment.
Product information
CAS Number: 1638970-43-0
Molecular Weight: 814.92
Formula: C46H50N6O8
Chemical Name: (2S)-2-[(2S)-2-[(2S)-2-[7-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)heptanamido]propanamido]propanamido]-N-(4-hydroxyphenyl)-N'-(triphenylmethyl)butanediamide
Smiles: C[C@H](NC(=O)[C@H](C)NC(=O)CCCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CC(=O)NC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)C(=O)NC1C=CC(O)=CC=1
InChiKey: XFPHUWWFIUTOLG-QXGWMLRCSA-N
InChi: InChI=1S/C46H50N6O8/c1-31(47-39(54)22-14-3-4-15-29-52-41(56)27-28-42(52)57)43(58)48-32(2)44(59)50-38(45(60)49-36-23-25-37(53)26-24-36)30-40(55)51-46(33-16-8-5-9-17-33,34-18-10-6-11-19-34)35-20-12-7-13-21-35/h5-13,16-21,23-28,31-32,38,53H,3-4,14-15,22,29-30H2,1-2H3,(H,47,54)(H,48,58)(H,49,60)(H,50,59)(H,51,55)/t31-,32-,38-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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