Parsaclisib (INCB050465) Hydrochloride


Catalog No. Size PriceQuantity
M17660-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Parsaclisib (INCB050465, IBI376) Hydrochloride is a potent and highly selective PI3Kδ(PI3K delta) inhibitor with an IC50 of 1 nM at 1 mM ATP in biochemical assay and approximately 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.

Product information

CAS Number: 1995889-48-9

Molecular Weight: 432.88

Formula: C20H22ClFN6O2

Chemical Name: 4-[3-(1-{4-amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethyl)-5-chloro-2-ethoxy-6-fluorophenyl]pyrrolidin-2-one

Smiles: CC1=NN(C(C)C2=CC(Cl)=C(F)C(C3CNC(=O)C3)=C2OCC)C2=NC=NC(N)=C12

InChiKey: ZQPDJCIXJHUERQ-UHFFFAOYSA-N

InChi: InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). DMSO: 94 mg/mL(200.28 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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