Description
Ac-IEPD-AFC is a substrate of Granzyme B.
Product information
CAS Number: 1135417-31-0
Molecular Weight: 725.67
Formula: C32H38F3N5O11
Chemical Name: 5-{2-[(2-carboxy-1-{[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]carbamoyl}ethyl)carbamoyl]pyrrolidin-1-yl}-4-(2-acetamido-3-methylpentanamido)-5-oxopentanoic acid
Smiles: CC(=O)NC(C(C)CC)C(=O)NC(CCC(O)=O)C(=O)N1CCCC1C(=O)NC(CC(O)=O)C(=O)NC1=CC2OC(=O)C=C(C=2C=C1)C(F)(F)F
InChiKey: HWXKKVLJPWMVLL-UHFFFAOYSA-N
InChi: InChI=1S/C32H38F3N5O11/c1-4-15(2)27(36-16(3)41)30(49)38-20(9-10-24(42)43)31(50)40-11-5-6-22(40)29(48)39-21(14-25(44)45)28(47)37-17-7-8-18-19(32(33,34)35)13-26(46)51-23(18)12-17/h7-8,12-13,15,20-22,27H,4-6,9-11,14H2,1-3H3,(H,36,41)(H,37,47)(H,38,49)(H,39,48)(H,42,43)(H,44,45)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
The Km of human granzyme B for Ac-IEPD-AFC in granzyme B assay buffer is 585 μM.
Products are for research use only. Not for human use.
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