Description
Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia.
Product information
CAS Number: 160492-56-8
Molecular Weight: 606.62
Formula: C35H41Cl2N3O2
Chemical Name: N-(1-{3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl}-4-phenylpiperidin-4-yl)-N-methylacetamide
Smiles: CN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)C2C=CC=CC=2)C2C=C(Cl)C(Cl)=CC=2)CC1)C1C=CC=CC=1
InChiKey: DZOJBGLFWINFBF-UMSFTDKQSA-N
InChi: InChI=1S/C35H41Cl2N3O2/c1-27(41)38(2)35(29-13-7-4-8-14-29)19-23-39(24-20-35)21-9-17-34(30-15-16-31(36)32(37)25-30)18-10-22-40(26-34)33(42)28-11-5-3-6-12-28/h3-8,11-16,25H,9-10,17-24,26H2,1-2H3/t34-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time. Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time.
Products are for research use only. Not for human use.
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