Description
LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist.
Product information
CAS Number: 925676-48-8
Molecular Weight: 335.34
Formula: C18H14FN5O
Chemical Name: N-[5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)pyrazin-2-yl]cyclopropanecarboxamide
Smiles: O=C(NC1=CN=C(C(=N1)C1C=NC=CC=1)C1=CC=NC=C1F)C1CC1
InChiKey: XUYURJQIMYCWBB-UHFFFAOYSA-N
InChi: InChI=1S/C18H14FN5O/c19-14-9-21-7-5-13(14)17-16(12-2-1-6-20-8-12)23-15(10-22-17)24-18(25)11-3-4-11/h1-2,5-11H,3-4H2,(H,23,24,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 125 mg/mL (372.76 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
At 3 mg/kg, LAS101057 is active in preventing Acetyl-β-methylcholine-induced AHR, and at 10 mg/kg it inhibits AHR to Acetyl-β-methylcholine to a level virtually equal to that seen with Hexadecadrol at 1 mg/kg.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.