Description
Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397. At 100 µM, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines.
Product information
CAS Number: 1086639-59-9
Molecular Weight: 265.15
Formula: C8H17BrN4O
Chemical Name: 1-(2-hydroxyethyl)-1,3,5,7-tetraazatricyclo[3.3.1.1³,⁷]decan-1-ium bromide
Smiles: [Br-].OCC[N+]12CN3CN(C1)CN(C2)C3
InChiKey: HBPXFHNNLMCUPA-UHFFFAOYSA-M
InChi: InChI=1S/C8H17N4O.BrH/c13-2-1-12-6-9-3-10(7-12)5-11(4-9)8-12;/h13H,1-8H2;1H/q+1;/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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