Description
CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation.
Product information
CAS Number: 2095280-64-9
Molecular Weight: 647.76
Formula: C38H41N5O5
Chemical Name: 4-tert-butyl-N-[2-methyl-3-(1-methyl-5-{[4-(morpholine-4-carbonyl)-3-(prop-2-enamido)phenyl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]benzamide
Smiles: CN1C=C(C=C(NC2=CC(NC(=O)C=C)=C(C=C2)C(=O)N2CCOCC2)C1=O)C1=CC=CC(NC(=O)C2C=CC(=CC=2)C(C)(C)C)=C1C
InChiKey: UBXBHXGYYBYXOB-UHFFFAOYSA-N
InChi: InChI=1S/C38H41N5O5/c1-7-34(44)40-32-22-28(15-16-30(32)36(46)43-17-19-48-20-18-43)39-33-21-26(23-42(6)37(33)47)29-9-8-10-31(24(29)2)41-35(45)25-11-13-27(14-12-25)38(3,4)5/h7-16,21-23,39H,1,17-20H2,2-6H3,(H,40,44)(H,41,45)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.