Description
NH-bis(m-PEG4) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 123852-08-4
Molecular Weight: 397.50
Formula: C18H39NO8
Chemical Name: 2,5,8,11,17,20,23,26-octaoxa-14-azaheptacosane
Smiles: COCCOCCOCCOCCNCCOCCOCCOCCOC
InChiKey: SHQDRKKVZPNSTN-UHFFFAOYSA-N
InChi: InChI=1S/C18H39NO8/c1-20-7-9-24-15-17-26-13-11-22-5-3-19-4-6-23-12-14-27-18-16-25-10-8-21-2/h19H,3-18H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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