Description
Bromo-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2167807-41-0
Molecular Weight: 335.21
Formula: C9H19BrO6S
Chemical Name: 2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}ethyl methanesulfonate
Smiles: CS(=O)(=O)OCCOCCOCCOCCBr
InChiKey: LUIMQGOWWSFHND-UHFFFAOYSA-N
InChi: InChI=1S/C9H19BrO6S/c1-17(11,12)16-9-8-15-7-6-14-5-4-13-3-2-10/h2-9H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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