VUT-MK142


Catalog No. Size PriceQuantity
M26041-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

VUT-MK142 is a potent new cardiomyogenic synthetic agent promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.

Product information

CAS Number: 1313491-22-3

Molecular Weight: 298.38

Formula: C17H22N4O

Chemical Name: N4-cyclohexyl-N6-(4-methoxyphenyl)pyrimidine-4,6-diamine

Smiles: COC1C=CC(=CC=1)NC1=CC(NC2CCCCC2)=NC=N1

InChiKey: YPIHLCLKUNREAT-UHFFFAOYSA-N

InChi: InChI=1S/C17H22N4O/c1-22-15-9-7-14(8-10-15)21-17-11-16(18-12-19-17)20-13-5-3-2-4-6-13/h7-13H,2-6H2,1H3,(H2,18,19,20,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 25 mg/mL (83.79 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

VUT-MK142 possesses promising cardiomyogenic effects on various cell types. VUT-MK142 shows a remarkable effect on both P19 and C2C12 cells. Compared to CgC, VUT-MK142-treatment leads to a markedly stronger up-regulation of the expression of ANF. VUT-MK142 (1 μM, 7 day treatment) significantly (p < 0.05) increases the luciferase signal by 3.1 ± 0.3 luciferase (n = 5)-fold in P19 cells.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed