[Nle11]-Substance P


Catalog No. Size PriceQuantity
M26178-C Contact sales@xcessbio.com for quotation $100

Description

[Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems.

Product information

CAS Number: 57462-42-7

Molecular Weight: 1329.59

Formula: C64H100N18O13

Chemical Name: 2-[(1-{6-amino-2-[(1-{2-amino-5-[(diaminomethylidene)amino]pentanoyl}pyrrolidin-2-yl)formamido]hexanoyl}pyrrolidin-2-yl)formamido]-N-[3-carbamoyl-1-({1-[(1-{[({1-[(1-carbamoylpentyl)carbamoyl]-3-methylbutyl}carbamoyl)methyl]carbamoyl}-2-phenylethyl)carbamoyl]-2-phenylethyl}carbamoyl)propyl]pentanediamide

Smiles: CC(C)CC(NC(=O)CNC(=O)C(CC1C=CC=CC=1)NC(=O)C(CC1C=CC=CC=1)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C1CCCN1C(=O)C(N)CCCN=C(N)N)C(=O)NC(CCCC)C(N)=O

InChiKey: ZEPTUBCWHRSMIP-UHFFFAOYSA-N

InChi: InChI=1S/C64H100N18O13/c1-4-5-22-42(54(69)86)75-58(90)46(34-38(2)3)74-53(85)37-73-55(87)47(35-39-17-8-6-9-18-39)79-59(91)48(36-40-19-10-7-11-20-40)80-57(89)43(26-28-51(67)83)76-56(88)44(27-29-52(68)84)77-60(92)50-25-16-33-82(50)63(95)45(23-12-13-30-65)78-61(93)49-24-15-32-81(49)62(94)41(66)21-14-31-72-64(70)71/h6-11,17-20,38,41-50H,4-5,12-16,21-37,65-66H2,1-3H3,(H2,67,83)(H2,68,84)(H2,69,86)(H,73,87)(H,74,85)(H,75,90)(H,76,88)(H,77,92)(H,78,93)(H,79,91)(H,80,89)(H4,70,71,72)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Substance P and its analog, [Nle11]-Substance P have shown similar potency in tests. The spasmogenic activity of Substance P and [Nle11]-Substance P are preserved in the same potency order on stimulated guinea-pig ileum.

Products are for research use only. Not for human use.

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