Description
(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis.
Product information
CAS Number: 199596-24-2
Molecular Weight: 308.76
Formula: C17H13ClN4
Chemical Name: 5-chloro-2-[(Z)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine
Smiles: ClC1=CN=C(C=C1)N/N=C(\C1=CC=CC=N1)/C1C=CC=CC=1
InChiKey: YHHFKWKMXWRVTJ-XLNRJJMWSA-N
InChi: InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 6 mg/mL (19.43 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
JIB-04 inhibits the demethylase activity of Jumonji enzymes in vitro and in cells, without affecting other α-ketoglutarate dependent hydroxylases or histone modifying enzymes .
Products are for research use only. Not for human use.
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