Z-LE(OMe)TD(OMe)-FMK


Catalog No. Size PriceQuantity
M28428-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Z-LE(OMe)TD(OMe)-FMK is a selective caspase-8 inhibitor. Z-LE(OMe)TD(OMe)-FMK can inhibit cell apoptosis.

Product information

CAS Number: 210344-93-7

Molecular Weight: 654.68

Formula: C30H43FN4O11

Chemical Name: methyl 3-{2-[2-(2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido)-5-methoxy-5-oxopentanamido]-3-hydroxybutanamido}-5-fluoro-4-oxopentanoate

Smiles: CC(C)CC(NC(=O)OCC1=CC=CC=C1)C(=O)NC(CCC(=O)OC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)OC)C(=O)CF

InChiKey: ARECPHKVCIQJRJ-UHFFFAOYSA-N

InChi: InChI=1S/C30H43FN4O11/c1-17(2)13-22(34-30(43)46-16-19-9-7-6-8-10-19)28(41)32-20(11-12-24(38)44-4)27(40)35-26(18(3)36)29(42)33-21(23(37)15-31)14-25(39)45-5/h6-10,17-18,20-22,26,36H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The apoptotic pathway activated after exposure of HL-60 cells to Cordycepin is caspase-8 dependent, because Z-LE(OMe)TD(OMe)-FMK partly inhibits endonucleosomal cleavage of DNA induced by cordycepin alone.

Products are for research use only. Not for human use.

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