(Rac)-Lanicemine


Catalog No. Size PriceQuantity
M30005-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.

Product information

CAS Number: 61890-25-3

Molecular Weight: 198.26

Formula: C13H14N2

Chemical Name: 1-phenyl-2-(pyridin-2-yl)ethan-1-amine

Smiles: NC(CC1=CC=CC=N1)C1C=CC=CC=1

InChiKey: FWUQWDCOOWEXRY-UHFFFAOYSA-N

InChi: InChI=1S/C13H14N2/c14-13(11-6-2-1-3-7-11)10-12-8-4-5-9-15-12/h1-9,13H,10,14H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (504.39 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Lanicemine produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects.Lanicemine (3, 10 or 30 mg/kg; intraperitoneal) not only engages brain circuits involved in the generation of gamma- electroencephalography (EEG), but also influences these networks independent of the broader systems-level disruptions typical of ketamine.

Products are for research use only. Not for human use.

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