Description
Benzyl-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 230620-73-2
Molecular Weight: 456.57
Formula: C24H40O8
Chemical Name: 2-[(1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl)oxy]oxane
Smiles: C(OCCOCCOCCOCCOCCOCCOC1CCCCO1)C1C=CC=CC=1
InChiKey: SMRNKNXGBFNGNB-UHFFFAOYSA-N
InChi: InChI=1S/C24H40O8/c1-2-6-23(7-3-1)22-30-19-18-28-15-14-26-11-10-25-12-13-27-16-17-29-20-21-32-24-8-4-5-9-31-24/h1-3,6-7,24H,4-5,8-22H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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