N-(5-Hydroxypentyl)maleimide


Catalog No. Size PriceQuantity
M32766-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ).

Product information

CAS Number: 180608-78-0

Molecular Weight: 183.20

Formula: C9H13NO3

Chemical Name: 1-(5-hydroxypentyl)-2,5-dihydro-1H-pyrrole-2,5-dione

Smiles: OCCCCCN1C(=O)C=CC1=O

InChiKey: YTIZONIKDWSRFR-UHFFFAOYSA-N

InChi: InChI=1S/C9H13NO3/c11-7-3-1-2-6-10-8(12)4-5-9(10)13/h4-5,11H,1-3,6-7H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker).

Products are for research use only. Not for human use.

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