Description
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ).
Product information
CAS Number: 180608-78-0
Molecular Weight: 183.20
Formula: C9H13NO3
Chemical Name: 1-(5-hydroxypentyl)-2,5-dihydro-1H-pyrrole-2,5-dione
Smiles: OCCCCCN1C(=O)C=CC1=O
InChiKey: YTIZONIKDWSRFR-UHFFFAOYSA-N
InChi: InChI=1S/C9H13NO3/c11-7-3-1-2-6-10-8(12)4-5-9(10)13/h4-5,11H,1-3,6-7H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker).
Products are for research use only. Not for human use.
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