(S)-AM-5308


Catalog No. Size PriceQuantity
M33718-C Contact sales@xcessbio.com for quotation $100

Description

(S)-AM-5308 (compound 7-13) is a potent kinesin KIF18A inhibitor with an IC50 of 46 nM for KIF18A ATPase. (S)-AM-5308 has the potential for cancer research

Product information

CAS Number: 2446340-45-8

Molecular Weight: 529.65

Formula: C26H35N5O5S

Smiles: C[C@H]1CN(CCO1)C1=CC=CC(NC(=O)C2=CC=C(C=C2N2CCC3(CC2)CC3)NS(=O)(=O)CCO)=N1

InChiKey: IUDCFCQNVQWCCI-IBGZPJMESA-N

InChi: InChI=1S/C26H35N5O5S/c1-19-18-31(13-15-36-19)24-4-2-3-23(27-24)28-25(33)21-6-5-20(29-37(34,35)16-14-32)17-22(21)30-11-9-26(7-8-26)10-12-30/h2-6,17,19,29,32H,7-16,18H2,1H3,(H,27,28,33)/t19-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Nuria A. Tamayo, et al. Kif18a inhibitors. WO2020132651A1.

Products are for research use only. Not for human use.

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