XD14


Catalog No. Size PriceQuantity
M33934-C Contact sales@xcessbio.com for quotation $100

Description

XD14 is a potent BET inhibitor with antitumor effect. It binds to BRD2, BRD3, and BRD4 with Kds of 170, 380, and 160 nM, respectively.

Product information

CAS Number: 1370888-71-3

Molecular Weight: 421.51

Formula: C20H27N3O5S

Smiles: CC(=O)C1C(CC)=C(NC=1C)C(=O)NC1=CC(=CC=C1O)S(=O)(=O)N(CC)CC

InChiKey: DPBKLIVPNYGQQG-UHFFFAOYSA-N

InChi: InChI=1S/C20H27N3O5S/c1-6-15-18(13(5)24)12(4)21-19(15)20(26)22-16-11-14(9-10-17(16)25)29(27,28)23(7-2)8-3/h9-11,21,25H,6-8H2,1-5H3,(H,22,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Schäker-Hübner L, et al. 4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads. J Med Chem. 2021 Oct 14;64(19):14620-14646.

Products are for research use only. Not for human use.

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