Description
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentration-dependent manner, with a 50% reduction in desaturation at 0.03 mM YTX-465
Product information
CAS Number: 2225824-53-1
Molecular Weight: 458.51
Formula: C25H26N6O3
Chemical Name: N-(2-(4-(3-(1, 3-dimethyl-1H-indazol-6-yl)-1, 2, 4-oxadiazol-5-yl)piperidin-1-yl)-2-oxoethyl)benzamide
Smiles: CN1N=C(C)C2=CC=C(C=C12)C1N=C(ON=1)C1CCN(CC1)C(=O)CNC(=O)C1C=CC=CC=1
InChiKey: UNYSKYOVUXWBJG-UHFFFAOYSA-N
InChi: InChI=1S/C25H26N6O3/c1-16-20-9-8-19(14-21(20)30(2)28-16)23-27-25(34-29-23)18-10-12-31(13-11-18)22(32)15-26-24(33)17-6-4-3-5-7-17/h3-9,14,18H,10-13,15H2,1-2H3,(H,26,33)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Vincent BM, Tardiff DF, Piotrowski JS, Aron R, Lucas MC, Chung CY, Bacherman H, Chen Y, Pires M, Subramaniam R, Doshi DB, Sadlish H, Raja WK, Solís EJ, Khurana V, Le Bourdonnec B, Scannevin RH, Rhodes KJ. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31. doi: 10.1016/j.celrep.2018.11.028. PMID: 30517862.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.